Articles on General Cold Chain, Thermal Boxes, and Temp Indicators

Cold Chain in the News

Cold Chain Technologies (CCT) and CCT's and Engineering and Technical Services have been featured in numerous articles. Articles on general cold chain issues are shown below. Click on the links in the menu on the right to access articles on insulated shipping containers, and our temperature indicator, KoolWatch. Please contact us if you have any questions or would like more information.

Archived Articles - General Cold Chain

Raffaele Potami, Cold Chain Technologies, Holliston

Worcester Business Journal, August 2009

"Raffaele Potami recently joined Holliston-based Cold Chain Technologies as a senior mechancial engineer. He'll be working on special research and development projects for the company..."

Validation of the Thermal Modeling Process for Cold-Chain Shippers

PMPN Pharma-Bio Transport, Winter 2009

Excerpt:
"...Cold Chain Technologies’ (CCT) use of predictive thermal modeling … simulates multiple design scenarios to arrive at an optimal configuration before making prototypes and conducting chamber testing. A computer program used during the modeling process lets the user pass through a number of required steps, including analysis selection, geometry creating, element selection, boundary condition application, and program execution … This article discusses the thermal modeling validation process that is being undertaken by CCT to accomplish this task, along with some of its initial results..."

Tracking Cold-Chain Quality

Pharmaceutical and Medical Packaging News, November 2008

Excerpt:
"As pharmaceutical companies devote more attention to cold-chain logistics, transport product and solutions providers are stepping up specialized services to support safe product delivery and limit costs. Regulatory and best practice guidance will support quality and cost control as supply-chain partners work in concert to establish that product is appropriately handled, stored and transported, says Larry Gordon, president, Cold Chain Technologies (CCT; Holliston, MA)..."

Holliston Co. Opens Reno Plant

Worcester Business Journal, June 2008

"Cold Chain Technologies of Holliston is opening a new plant in Reno, Nevada and expanding its operations in Massachusetts and Tennessee..."

Bringing Cold Chain Shippers to Market Faster with Thermal Modeling

PMPN Pharma-Bio Transport , May 2008

By Richard M. Formato and Vikas Patel, Cold Chain Technologies

Excerpt:
"Predictive, or mathematical, modeling is the process whereby a set of mathematical relationships (the model) represents a real-life system based on certain approximations and assumptions. Finite Element Analysis (FEA) is one well-suited method of predictive modeling for complex modeling tasks requiring high accuracy..."

Maintaining the Cold Chain

Pharmaceutical Technology, March 2008

Excerpt:
"...Some suppliers of cold chain management products also provide testing, design, and certification services. Temperature studies can be done with dry ice, gel packs, or shipment simulation ... package qualification and testing, Cold Chain Technologies' Cold Chain Laboratories; cold-chain management validation and qualification services."

Put Temperature to the Test

PMPN Pharma-Bio Transport, February 2008

Excerpt:
"...Reducing those variables and decreasing the number of handoffs will mitigate product risks, asserts Donald Nolde, vice president of sales and marketing, Cold Chain Technologies (Holliston, MA). 'The fewer people handling product, the better off you'll be,' says Nolde, whose company specializes in cold-chain shipping containers...' Our task at Cold Chain is to make their job easier and with better compliance by providing improved and simplified packaging solutions."

Forecast for the Cold Chain

Pharmaceutical & Medical Packaging News, November 2007

Excerpt:
"Cold Chain Technologies (CCT; Holliston, MA) has extended its KoolTemp GTS (global transport system) line of pre-qualified shippers with the KoolTemp GTS-5420 Pallet Shipper..."

Prequalified Solutions Target Pharma Transport

Pharmaceutical & Medical Packaging News, September 2007

Excerpt:
"Cold Chain Technologies (Holliston, MA) has partnered with Topa Verpakking B.V. (The Netherlands), a provider of cold-chain solutions throughout Europe. Topa Verpakking will supply KoolTemp containers (EPS, PUR) and Koolit refrigerants (bricks, gels, mats) to the European market. Working together, the labs of these firms will provide equivalent design and qualification testing on both sides of the Atlantic..."

Warm Euro Welcome for Cold Chain Shipping Co.

Worcester Business Journal, June 2007

"A new partnership with a company in the Netherlands allows Holliston-based Cold Chain Technologies to sell its products throughout Europe..."

All Aboard the Cold Chain

Pharmaceutical Manufacturing Magazine, October 2005

Excerpt:

"Food and other perishable products have been shipped for years over long distances, begging the question: Why the fuss about pharmaceuticals?

'The main difference between food and drug shipments is dollars and cents," notes : Cold Chain Technologies (Holliston, Mass.). "When Purdue Farms sends out a reefer [refrigerated tractor trailer] and someone forgets to flip a switch, they lose $15,000 worth of chickens. When the same thing happens to a pharmaceutical shipment, the loss may be in the millions of dollars, not to mention potentially adulterated product slipping through to consumers.'"

Taking the Costs Out of Thermal Packaging: Thermal transportation professionals are striving for longer shipping windows, lower dimensional weight, and ease of packout, while meeting customer demands for tight temperature control

Pharmaceutical & Medical Packaging News, October 2005

"The increasing prevalence of drugs and medical devices requiring thermal protection during shipping has fueled interest in higher-performance packaging solutions:

For instance, Cold Chain Technologies Inc. (Holliston, MA) uses 0° Koolit foam bricks and polyurethane in its newest line of KoolTemp PUR containers. The KoolTemp Global Transportation Solution (GTS) prequalified shipper contains frozen and refrigerated bricks to maintain 2° - 8°C temperatures for 48 hours under year-round conditions. 'The GTS allows the same exact conditioning and packout for summer and winter. The packout is easy and quick using our Koolit foam bricks,' (according to Cold Chain Technologies)..."

Phase-Change Materials Cut the Ice

Pharmaceutical & Medical Packaging News, February 2005

Excerpt:

"For decades, those shipping refrigerated temperature-sensitive products had their choice of two phase-change points: 0°C (water) or -80°C (dry ice)...

Cold Chain manufactures paraffin-based PCMs, but Gordon (President of Cold Chain Technologies) acknowledges that their biggest drawback is price. 'They are an order of magnitude higher in price that a standard refrigerant gel. As a result, we have found that we are often able to meet the needs of our customers in a more efficient and economical way without the use of paraffins.'

Another problem, though, according to Gordon, is that "hydrated salts tend to be unstable. If you run them through a phase change, they do not always perform the same way the second or third time around. This makes for some difficult reproducibility when considering qualification testing for pharmaceuticals. One reason is their tendency to precipitate, meaning that the solids of the salt reform and come out of solution." Precipitation changes the molarity of the solution and thus alters the temperature at which phase change occurs."

Oh, Gee...MP

Packaging World Magazine, November 2004

Excerpt:

"Concerns about food processing sanitation may lead to packaging and labeling changes, especially for allergens...

... (Cold Chain Technologies) thinks food companies would rebel against any effort by the FDA to mandate use of TTIs. 'They don't want the FDA to tell them how to run their business,' he explains. Cold Chain sells its own TTIs, plus those manufactured by companies such as Temptime Corp. and 3M Company. These can cost anywhere from $1.50 to $4. per tag. They make radio-frequency identification (RFID) tags look positively cheap."

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Cold Chain in the News

Archived Articles - General Cold Chain

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